Home › Travel

By Victoria Nguyen•Last Updated August 31, 2025

Epic Backpacking Routes Across South America: Itineraries, Guidance, and Key Destinations

Photo by Kristen Plastique on Unsplash

Introduction

South America offers some of the most diverse and breathtaking backpacking routes in the world, drawing travelers with its rich cultures, dramatic landscapes, and iconic hiking opportunities. Whether you seek the classic Gringo Trail, multi-day wilderness treks, or a custom journey across the continent, this guide provides actionable steps and verified advice to help you plan and execute your adventure. All information is based on reliable, accessible sources, with guidance on route selection, logistics, budgeting, and local resources.

Major Backpacking Routes in South America

Several established routes offer backpackers efficient ways to experience South America’s highlights, each with distinct advantages and practical considerations.

The Gringo Trail

The Gringo Trail is the continent’s most famous backpacking route, covering top destinations from Colombia through Ecuador, Peru, Bolivia, Chile, and Argentina [2] . This route allows travelers to experience cloud forests, Inca ruins, salt flats, deserts, wine regions, and cosmopolitan cities in a logical sequence. The flexibility of the trail means you can adjust your itinerary based on interests, time, and budget.

Example itinerary:

Colombia: Explore BogotÃ¡, MedellÃn, Cartagena, and the coffee region. Trek to the Lost City (Ciudad Perdida) for a multi-day jungle adventure [3] .
Ecuador: Visit Quito, Otavalo, BaÃ±os, and the Amazon. Hike in the cloud forests and consider a trip to the GalÃ¡pagos Islands (advance planning and budgeting required).
Peru: Tour Lima, Cusco, and trek to Machu Picchu via the Classic Inca Trail or alternative routes. Try the Ausangate + Rainbow Mountain Circuit for remote high-altitude hiking [3] .
Bolivia: Visit La Paz, the Valley of the Moon, ride Death Road, and experience the Uyuni Salt Flats with possible camping under the stars [1] .
Chile: Base yourself in San Pedro de Atacama for desert landscapes and stargazing, then continue to Santiago for urban culture and wine tours. Patagonia offers world-class hiking, such as the W Trek in Torres del Paine.
Argentina: Enjoy Buenos Aires, hike the Fitz Roy Loop at El ChaltÃ©n, and explore glaciers near El Calafate [5] .

The Super Loop and Alternative Routes

The Super Loop offers a circular route for those seeking less-traveled regions, including northern Brazil, Paraguay, and Uruguay. While less popular, this approach can reveal hidden gems and unique local experiences. Always check local transportation options and regional safety advisories before planning your route [2] .

Multi-Day Treks and Hiking Adventures

South America boasts several iconic multi-day hikes for backpackers who wish to immerse themselves in its natural wonders. Popular treks include:

Ausangate + Rainbow Mountain Circuit (Peru): A remote, high-altitude trek near Cusco, featuring dazzling landscapes and unique wildlife. Suitable for experienced hikers [3] .
W Trek (Torres del Paine, Chile): This 4-5 day hike traverses Patagonia’s iconic mountains, lakes, and glaciers. Campsites and refugios (mountain huts) can be reserved in advance with local operators.
Fitz Roy Loop (El ChaltÃ©n, Argentina): A 2-3 day circuit showcasing Fitz Roy peak, Cerro Torre, and glacier lakes. The hike begins and ends in El ChaltÃ©n, a town known for its welcoming trekking community [3] .
Lost City Trek (Colombia): A 5-day jungle trek to ancient ruins in the Sierra Nevada, accessible from Santa Marta. The journey requires local guides and involves sleeping in basic campsites [3] .

For each trek, research the current season, required permits, and recommended gear. Local tourism offices and established trekking companies can provide updated information and assist with bookings.

Planning and Logistics

Efficient planning is key to a successful backpacking trip in South America. Consider the following steps:

Visa and Entry Requirements

Check the entry requirements for each country you plan to visit. Most South American countries welcome tourists for 30-90 days without a visa, but some may require proof of onward travel or vaccinations. Consult the official embassy websites for the latest updates.

Budgeting and Costs

Backpacking costs vary by country and region. Colombia, Bolivia, and Ecuador are generally the most affordable, while Chile, Argentina, and Brazil can be more expensive. Budget travelers can expect to spend $25-$50 per day, depending on accommodation, food, and activities [4] . Use local buses for long-distance travel and seek hostel or guesthouse accommodation to maximize savings.

Transportation

South America’s extensive bus networks connect major cities and tourist destinations. Research reputable bus operators in each country, and book tickets at local terminals or through verified travel agencies. For remote regions, domestic flights may save time but can be more expensive. Always confirm schedules and availability in advance.

Local options such as colectivos (shared vans) and motorcycle taxis are common for short distances. In major cities, use officially registered taxis or ride-sharing apps where available.

Safety and Health

While South America is generally safe for backpackers, some regions require extra caution. Avoid displaying valuables, stay aware in crowded areas, and follow local advice on travel advisories. Comprehensive travel insurance is highly recommended [2] . For health, consult the CDC website for recommended vaccinations and preventive medications (such as malaria prophylaxis for Amazon regions).

Accessing Local Resources and Opportunities

To maximize your experience and access local services:

Visit official tourism offices in major cities for maps, guides, and current events.
Use verified platforms such as Hostelworld or Booking.com for accommodation searches. When uncertain, ask for recommendations at local hostels or guesthouses.
Engage with local trekking companies for guided hikes and permit assistance. Confirm company credentials before booking.
Join online backpacker communities (such as Lonely Planet’s Thorn Tree forum) for up-to-date tips and travel companions.
Consider learning basic Spanish to facilitate travel and enhance safety.

If you wish to book tours or transportation, research the provider’s reputation and use official websites or physical offices. Avoid making payments to unverifiable sources, especially for high-value services such as guided treks or domestic flights.

Step-by-Step Implementation Guidance

1. Define Your Route: Choose a major trail (Gringo Trail, Super Loop) or create a custom itinerary based on your interests and timeframe.

2. Research Entry Requirements: Visit each country’s embassy website for visa and health regulations.

3. Budget and Save: Estimate daily costs using recent backpacker reports. Plan for additional expenses such as treks, tours, and flights.

4. Book Essential Services: Reserve hostels or guesthouses in advance during peak seasons. Secure trekking permits and hire guides where required.

5. Pack Appropriately: Prepare for diverse climates: from humid jungles to high-altitude mountains. Waterproof gear, sturdy boots, and layered clothing are recommended.

6. Stay Informed: Regularly check official tourism, embassy, and health websites for current travel advisories.

7. Engage Locally: Attend community events, use public transportation, and support local businesses for a more authentic experience.

8. Be Flexible: Road closures, weather, and local events may require itinerary changes. Always have backup plans and alternative routes.

Potential Challenges and Solutions

Travelers may encounter logistical challenges such as transport delays, language barriers, and rapidly changing weather. Solutions include:

Building extra days into your itinerary for unforeseen delays.
Using translation apps and learning essential Spanish phrases.
Monitoring weather forecasts and adjusting plans accordingly.
Joining group tours for increased safety in remote regions.

Alternative Approaches

If classic routes are crowded or unavailable, consider lesser-known regions such as Paraguay, Uruguay, or northern Brazil. These areas are increasingly accessible and offer unique cultural and natural experiences. Always consult official tourism boards for current information.

Summary and Key Takeaways

Backpacking across South America is a rewarding journey when well-planned and informed by verified resources. Choose your route, prepare thoroughly, and remain flexible to adapt to local conditions. For services and bookings, use only reputable, accessible providers, and rely on official guidance when uncertain. With the right approach, you can experience the continent’s natural wonders, vibrant cultures, and adventure opportunities to the fullest.